In 2025, the United States continues to lead the world in cutting-edge fertility treatments. With hundreds of IVF (In Vitro Fertilization) clinics across the country, choosing the right one can feel overwhelming.
Whether you’re struggling with infertility, considering IVF for single parenting or LGBTQ+ family building, or seeking donor egg/sperm services, selecting the right clinic is key to your success.
This comprehensive guide covers the best IVF clinics in the USA in 2025, based on success rates, affordability, treatment options, technology, and real patient reviews.
It also includes a breakdown of average IVF costs, insurance options, and how to choose a fertility clinic that fits your needs.
What Makes an IVF Clinic the Best?
While every individual’s fertility journey is different, the best IVF clinics typically share these core attributes:
- High live birth rates per IVF cycle
- Accreditation by SART and CDC (Society for Assisted Reproductive Technology & Centers for Disease Control)
- Personalized treatment plans
- Transparent pricing and package options
- Inclusive services for all family types
- Modern labs use AI, genetic testing, and advanced freezing techniques
Top 10+ Best IVF Clinics in the USA (2025)
1. CCRM Fertility – Multiple Locations Nationwide
Flagship Locations: Colorado, New York, Boston, Houston, San Francisco
Success Rate (Women under 35): ~74% live births per embryo transfer
IVF Package Price: Starts at $18,000 (excluding medications)
Why They Stand Out:
CCRM is one of the most respected names in fertility. Founded by renowned reproductive endocrinologist Dr. William Schoolcraft, the clinic is known for its cutting-edge labs, advanced preimplantation genetic testing (PGT), and extremely high success rates.
Patient Review:
“After 2 failed rounds at another clinic, CCRM helped us conceive on the first try. The care was professional, warm, and thorough.”
2. Shady Grove Fertility – East Coast & Nationwide
Headquarters: Rockville, Maryland
Success Rate: ~68% for women under 35
IVF Costs: Starts around $13,000; Shared Risk Refund Plans available
Why Choose SGF:
One of the largest fertility networks in the U.S., SGF is known for its affordable IVF refund programs, egg donor bank, and LGBTQ+ inclusive services.
Special Programs:
- 100% refund guarantee (if no live birth)
- Egg Freezing and Donor Egg Programs
- International patient concierge
Review Highlight:
“The shared risk program made IVF financially doable for us. Excellent communication and care!”
3. RMA Network (Reproductive Medicine Associates)
Key Clinics: RMA of New Jersey, RMA of New York, RMA of Southern California
Success Rate: 70-78% (depending on location and age)
IVF Price: Around $15,000–$20,000 per cycle
Highlights:
RMA clinics are known for their embryo culture systems, embryo scoring with AI, and world-class labs. Their robust research backing ensures evidence-based care.
Good For:
Couples facing repeated IVF failure, advanced maternal age, or recurrent miscarriage.
4. NYU Langone Fertility Center – New York City, NY
Success Rate: 71% live birth rate (under 35)
IVF Cost: $17,500 + $3,000–$5,000 for medications
Why It’s Ranked High:
NYU Langone offers academic-level care, access to clinical trials, and leading fertility specialists in a city known for its elite medical institutions.
Top Features:
- PGT-A testing
- Egg and embryo freezing
- Male infertility diagnosis
5. Pacific Fertility Center – San Francisco, CA
Success Rate: 70% (under 35)
IVF Cost: ~$19,000 per cycle, not including meds
Known For:
High success rates, especially for older women and LGBTQ+ couples. The lab is affiliated with Prelude Fertility and uses time-lapse embryo monitoring.
International Friendly:
Frequently serves patients from China, Europe, and Latin America.
6. Boston IVF – Massachusetts, Maine, Rhode Island, and more
Success Rate: ~65% (under 35)
IVF Cost: ~$14,000 + meds; payment plans available
Why Patients Love It:
Boston IVF partners with Harvard Medical School and Beth Israel Deaconess, offering an academic yet personalized approach.
Highlights:
- Acupuncture integration
- Male fertility center
- Fertility preservation (cancer patients, elective egg freezing)
7. Northwestern Fertility and Reproductive Medicine – Chicago, IL
Affiliation: Northwestern University Feinberg School of Medicine
Success Rate: ~72% (under 35)
Why It’s on the List:
Combines elite academic care with patient-first support. Ideal for PCOS, endometriosis, and high-risk patients.
Patient Feedback:
“I felt heard every step of the way. Their thorough approach gave me hope after years of trying.”
8. HRC Fertility – Southern California
Locations: Pasadena, Newport Beach, Encino, West LA
Success Rate: ~68–75%
Costs: $12,000–$17,000 per cycle, add-ons extra
Good For:
Diverse clientele, especially same-sex couples, international surrogacy, and single parents.
Special Features:
- Gender selection
- Donor egg and sperm banks
- Bilingual staff
9. San Diego Fertility Center – California
Success Rate: ~70%
Known For:
Global destination for IVF with a stellar reputation for international patient support, egg donation, and surrogacy.
Packages:
- IVF with donor egg
- IVF with surrogate coordination
- Embryo donation
10. Oregon Reproductive Medicine – Portland, OR
Success Rate: 77% (among highest in the country for fresh embryo transfer)
Costs: ~$20,000+ per cycle; bundle packages available
Why It’s Exceptional:
ORM’s in-house genetics team offers advanced embryo screening, donor matching, and fertility genomics.
Top Choice For:
International IVF, LGBTQ+ families, and high-tech fertility treatments.
11. Houston Fertility Institute – Texas
Success Rate: ~68% (under 35)
Affordable IVF Options: Starting at $9,000–$12,000
Why It’s Listed:
Combines affordability with strong outcomes, making it great for middle-income families or cash-pay patients.
IVF Costs in the USA in 2025
| Cost Category | Average Price (USD) |
|---|---|
| One IVF Cycle | $12,000 – $20,000 |
| Fertility Medications | $3,000 – $6,000 |
| PGT-A Genetic Testing | $4,000 – $6,000 |
| Embryo Freezing | $1,000 – $2,500 |
| Storage (Annual) | $500 – $1,200 |
| Donor Egg IVF | $25,000 – $40,000+ |
| Surrogacy IVF Package | $80,000 – $150,000+ |
IVF Success Rates in the USA (2025)
According to the latest CDC and SART data, the national average live birth rates per embryo transfer:
- Women <35: 65–75%
- Women 35–37: 55–65%
- Women 38–40: 40–55%
- Women 41–42: 25–35%
- Women >42: 10–20%
Note: Success depends on embryo quality, uterine health, age, and lifestyle factors. Clinics with high rates also tend to be more selective with patients and transfer fewer embryos.
LGBTQ+, Single Parent & Surrogacy Friendly IVF Clinics
The best IVF clinics now openly support all family types, offering donor sperm, donor eggs, and surrogacy coordination. Top-rated clinics for inclusive care include:
- San Diego Fertility Center
- HRC Fertility
- CCRM
- ORM Fertility (Portland)
- Shady Grove Fertility
How to Choose the Right IVF Clinic
- Verify Accreditation
Look for SART, CDC, and ASRM listings. - Understand the Pricing
Ask for full-cycle pricing + hidden costs like meds and genetic testing. - Review Success Rates for Your Age
Don’t just look at averages—ask for success rates relevant to you. - Evaluate Emotional Support
Look for clinics offering therapy, counseling, or fertility coaching. - Read Verified Reviews
Patient testimonials often reveal how staff treat patients during tough moments.
IVF Refund and Financing Options (2025)
Many clinics now offer:
- 100% Money-Back IVF Programs if no baby is born
- Multi-cycle discounts
- Third-party financing (CapexMD, Future Family, Ally)
- HSAs and FSAs for tax-free fertility funding
Final Thoughts: Which IVF Clinic is Right for You?
The best IVF clinic in the USA for you isn’t just the one with the highest success rate—it’s the one that understands your unique journey, supports you with compassion, and helps you achieve parenthood with confidence.
Take your time to research, interview doctors, compare packages, and trust your instincts.
